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A detailed study of gold-nanoparticle loaded cells using X-ray based techniques for cell-tracking applications with single-cell sensitivity

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Nanoscale, 2013, Advance Article
DOI: 10.1039/C3NR34089A, Paper
Alberto Astolfo, Fulvia Arfelli, Elisabeth Schultke, Simon James, Lucia Mancini, Ralf-Hendrik Menk
Complementary imaging techniques on different length scales assess properties of intracellular nano-particulate imaging probes incorporated via endocytosis to elucidate limits and potentials of X-ray CT based cell tracking. Cells loaded with sufficient gold nanoparticles (a) can be resolved in vitro (b) and ex vivo (c) using a microCT scanner.
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