Surface charge of polymer coated SPIONs influences the serum protein adsorption, colloidal stability and subsequent cell interaction in vitro

Nanoscale, 2013, 5,3723-3732
DOI: 10.1039/C2NR33134A, Paper

Vera Hirsch, Calum Kinnear, Marc Moniatte, Barbara Rothen-Rutishauser, Martin J. D. Clift, Alke Fink
SPIONs with different surface charges elicit different cellular uptake albeit with very similar protein adsorption patterns and zeta-potentials after incubation in biological fluids. This can be explained by consideration of colloidal stability and underlying surface charge.
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