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Nanostructured TiO2 surfaces promote polarized activation of microglia, but not astrocytes, toward a proinflammatory profile

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Nanoscale, 2013, Advance Article
DOI: 10.1039/C3NR03534D, Paper
Silvia De Astis, Irene Corradini, Raffaella Morini, Simona Rodighiero, Romana Tomasoni, Cristina Lenardi, Claudia Verderio, Paolo Milani, Michela Matteoli
Nanostructured substrates are able, exclusively in virtue of their physical properties and depending on the graded nanoscale rugosity, to push microglia toward a proinflammatory activation phenotype.
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