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Drug-loaded nanoparticles induce gene expression in human pluripotent stem cell derivatives

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Nanoscale, 2014, Advance Article
DOI: 10.1039/C3NR04794F, Paper
Virendra Gajbhiye, Leah Escalante, Guojun Chen, Alex Laperle, Qifeng Zheng, Benjamin Steyer, Shaoqin Gong, Krishanu Saha
Doxycycline (DXC), a transgene inducer, was conjugated to PEGlyated hyperbranched polymers (H40); DXC-conjugated nanoparticles controlled gene expression in stem-cell-derived fibroblasts.
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